Dear,
I don`t think in standard it is possibel.
Workaround:
But at the time of creation of P.O you can deactivate check box" Info update" in item details-->Material data.
To set this automatic deactivation of "Info update" chcek box for your desired P.O document type, you can take ABAPER help and make the check box inactive while saving the P.O.
Hope this may help you.
Regards,
Pardhu